Implikasi steroid saponin dan sapogenins dalam efek hypocholesterolemic fenugreek.

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Implikasi steroid saponin dan sapogenins dalam efek hypocholesterolemic fenugreek.

Sauvaire, Y., Ribes, G., Baccou, JC, dan Loubatieres-Mariani, MM (1991). Implikasi steroid saponin dan sapogenins dalam efek hypocholesterolemic fenugreek. Lipid. 26, 191-197.

Transformasi fenugreek subfractions, kaya steroid saponin, dipelajari pada bagian mereka melalui saluran pencernaan untuk menentukan kontribusi saponin dan / atau diosgenin dan sapogenins ke efek hypocholesterolemic biji fenugreek. Alloxan diabetes kotoran anjing makan fenugreek pengurangan dianalisis, dan diosgenin, smilagenin dan gitogenin diidentifikasi dan diukur dengan menggunakan kromatografi gas kapiler / spektrometri massa. Hasil kami menunjukkan bahwa saponin, di bagian (sekitar 57%) dihidrolisis ke sapogenins dalam saluran pencernaan. Tampak bahwa saponin dapat terlibat, sendirian atau bersama-sama dengan diosgenin, dalam mengamati efek hypocholesterolemic biji fenugreek diabetes anjing.

Implications of steroid saponins and sapogenins in the hypocholesterolemic effect of fenugreek.

Sauvaire, Y., Ribes, G., Baccou, J.C., and Loubatieres-Mariani, M.M. (1991). Implications of steroid saponins and sapogenins in the hypocholesterolemic effect of fenugreek. Lipids. 26, 191-197.

The transformation of fenugreek subfractions, rich in steroid saponins, was studied upon their passage through the digestive tract to determine the contribution of saponins and/or diosgenin and other sapogenins to the hypocholesterolemic effect of fenugreek seeds. Feces of alloxan diabetic dogs fed fenugreek subtractions were analyzed, and diosgenin, smilagenin and gitogenin were identified and measured using capillary gas chromatography/mass spectrometry. Our results show that saponins are, in part (about 57%) hydrolyzed into sapogenins in the digestive tract. It appears that saponins may be implicated, alone or together with diosgenin, in the observed hypocholesterolemic effect of fenugreek seeds in diabetic dogs.