BUKTI ILMIAH HULBAH / FENUGREEK SANGAT AMPUH MENCEGAH DAN MENGOBATI DIABETES

Penelitian telah dialkukan sepanjang waktu untuk membuktikan jika fenugreek / hulbah benar - benar ampuh dan aman untuk mencegah dan mengobati diabetes, sebagaian dari hasil penelitian tersebut misalnya adalah :

1. Improved alpha-amylase and Helicobacter pylori inhibition by fenugreek extracts derived via solid-state bioconversion using Rhizopus oligosporus Asia Pac J Clin Nutr. 2007; 16(3):382-92.
2. Effect of Trigonella foenum-graecum (fenugreek) extract on blood glucose, blood lipid and hemorheological properties in streptozotocin-induced diabetic rats. Asia Pac J Clin Nutr. 2007; 16 Suppl 1:422-6.
3. Soluble dietary fibre fraction of Trigonella foenum-graecum (fenugreek) seed improves glucose homeostasis in animal models of type 1 and type 2 diabetes by delaying carbohydrate digestion and absorption, and enhancing insulin action. Br J Nutr. 2007 Mar; 97(3):514-21.
4. In vivo effect of Trigonella foenum graecum on the expression of pyruvate kinase, phosphoenolpyruvate carboxykinase, and distribution of glucose transporter (GLUT4) in alloxan-diabetic rats. Can J Physiol Pharmacol. 2006 Jun;84(6):647-54.
5. Long-term effect of Trigonella foenum graecum and its combination with sodium orthovanadate in preventing histopathological and biochemical abnormalities in diabetic rat ocular tissues. Mol Cell Biochem. 2006 Sep; 289(1-2):137-47. Epub 2006 May 23.
6. Low doses of vanadate and Trigonella synergistically regulate Na+/K + -ATPase activity and GLUT4 translocation in alloxan-diabetic rats. Mol Cell Biochem. 2006 Apr;285(1-2):17-27. Epub 2006 Apr 19.
7. Modulation of glucose transporter (GLUT4) by vanadate and Trigonella in alloxan-diabetic rats. Life Sci. 2006 Jan 18;78(8):820-4. Epub 2005 Nov 14.
8. Effect of supplementation of traditional medicinal plants on blood glucose in non-insulin-dependent diabetics: a pilot study. J Med Food. 2005 Winter;8(4):545-9.
9. Restoration of ultrastructural and biochemical changes in alloxan-induced diabetic rat sciatic nerve on treatment with Na3VO4 and Trigonella–a promising antidiabetic agent. Mol Cell Biochem. 2005 Oct; 278(1-2):21-31.
10. Supplementation of fenugreek leaves reduces oxidative stress in streptozotocin-induced diabetic rats. J Med Food. 2005 Fall;8(3):382-5.
11. Modulatory effect of fenugreek seed mucilage and spent turmeric on intestinal and renal disaccharidases in streptozotocin induced diabetic rats. Plant Foods Hum Nutr. 2005 Jun; 60(2):87-91.
12. The hypoglycaemic activity of fenugreek seed extract is mediated through the stimulation of an insulin signalling pathway. Br J Pharmacol. 2005 Sep; 146(1):41-8.
13. Trigonella foenum graecum seed powder protects against histopathological abnormalities in tissues of diabetic rats. Mol Cell Biochem. 2004 Nov; 266(1-2):151-9.
14. Genotoxicity testing of a fenugreek extract. Food Chem Toxicol. 2004 Nov; 42(11):1769-75.
15. Supplementation of fenugreek leaves lower lipid profile in streptozotocin-induced diabetic rats. J Med Food. 2004 Summer; 7(2):153-6.
16. Supplementation of fenugreek leaves to diabetic rats. Effect on carbohydrate metabolic enzymes in diabetic liver and kidney. Phytother Res. 2003 Dec; 17(10):1231-3.

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